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STATEMENT: MAPS-Funded Phase 3 Research Reports Results from Long-Term Observational Follow-Up Study on MDMA-Assisted Therapy for PTSD

Apr 5, 2023

Interim results show improvements in PTSD symptom severity lasted at least six months after the last treatment session.

Article is originally published by MAPS.org. To read the original article and to find out more click here.


FOR IMMEDIATE RELEASE: April 5, 2023


  • Interim results show improvements in PTSD symptom severity lasted at least six months after the last treatment session


MAPS Public Benefit Corporation (MAPS PBC), a wholly-owned subsidiary of the Multidisciplinary Association for Psychedelic Studies (MAPS),  announced preliminary findings from the observational study Long-Term  Safety and Persistence of Effectiveness of Manualized MDMA-Assisted  Therapy for the Treatment of Posttraumatic Stress Disorder (MPLONG).  According to MAPS PBC, these preliminary findings “show that  participants in this study demonstrated a durable response at least six  months, and in some cases a year or more, after their final  MDMA-assisted therapy session during the Phase 3 study.”


The first long-term observational follow-up analysis of six pooled phase 2 trials, published in Psychopharmacology in 2020, demonstrated that the treatment effects were sustained for at least one year following the treatment sessions.


"MDMA-assisted therapy is initially intensive — for both participants  and practitioners — because it’s a process that seeks to treat root  causes rather than just minimize symptoms. While patients and  practitioners need to know the treatment effects could be long-lasting  to invest their time, insurers need to understand the same to provide  coverage. The results of this follow-up study suggest the durability of  treatment results and the financial viability of MDMA-assisted therapy  for PTSD."


- Rick Doblin, Ph.D., Founder and President, MAPS

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